Programming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity

TitleProgramming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity
Publication TypeJournal Article
Year of Publication2017
Authors, NJ Carroll, M Rubinstein, A Chilkoti, and GP López
JournalNat Chem
Pagination509 - 515
Date Published01/2017
Abstract

A programmable model of membraneless organelles comprised of intrinsically disordered proteins (IDPs) containing sequences of low complexity has now been developed. The rules governing the assembly of archetypal IDPs into biologically inspired mixed, layered and size-controlled configurations provides a new means for understanding intracellular phase behaviour of IDPs.

DOI10.1038/nchem.2715
Short TitleNat Chem