Programming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity

Abstract

A programmable model of membraneless organelles comprised of intrinsically disordered proteins (IDPs) containing sequences of low complexity has now been developed. The rules governing the assembly of archetypal IDPs into biologically inspired mixed, layered and size-controlled configurations provides a new means for understanding intracellular phase behaviour of IDPs.

DOI
10.1038/nchem.2715
Year